AWS HealthOmics now supports Nextflow version pinning at run time

AWS HealthOmics has introduced runtime version pinning for Nextflow workflows, allowing customers to specify which Nextflow engine version to use when executing bioinformatics workflows through the StartRun API. The new engine-settings parameter supports multiple Nextflow versions including 22.04, 23.10, 24.10, 25.10, and 26.04, giving users explicit control over workflow execution environments without requiring modifications to the underlying workflow source code. This capability addresses a critical need in regulated healthcare and life sciences environments where pipeline validation is mandatory before adopting new engine versions. The runtime override takes precedence over any version specifications in the workflow's manifest configuration, enabling organizations to maintain production workflows on validated engine versions while development teams test newer versions in parallel. This approach reduces the risk of unexpected behavior changes and supports controlled migration strategies for mission-critical bioinformatics pipelines. The feature is now available across all AWS HealthOmics regions, including US East and West, multiple European regions, Israel, and Asia Pacific locations. AWS HealthOmics is positioned as a HIPAA-eligible service designed to accelerate scientific research through fully managed bioinformatics workflows at scale.